This application note describes a process for adenovirus production, from upstream cell culture to downstream purification, using modern tools and technologies.
Critical quality attributes (CQA) are fundamental to regulatory compliance and in drug development and manufacturing. Find out how surface plasmon resonance has been applied for protein characterization of antibody effector function.
Understand the important factors you need to consider when selecting lateral flow device (LFD) components to design an LFD to fit your needs.
Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.
Validating host cell protein ELISAs is an essential part of biologics development. But what makes these coverage assays so vital, and what could we improve? Read how this 2D DIBE approach combines the best of existing methods.
Critical quality attributes (CQA) are fundamental to regulatory compliance and typically include data on how the candidate interacts with target proteins, size, and purity. In addition, information on process related CQA such as protein integrity, homogeneity, presence of host cell proteins, and DNA is required. This poster booklet provides a snapshot on how different analytical technologies have been used to look into aspects related to the efficacy, stability, and safety of therapeutic candidates.
Soil testing laboratories need to operate cost effectively while maintaining accuracy and reliability. Efficient filtration plays a key part in this as a first step in sample preparation before analysis. A laboratory that can make sure it is using optimum filtration practices and materials can simplify soil testing workflows, provide accurate and reliable results, and maximize its profitability.
Although it is still challenging to gauge the full extent of the consequences of air pollution, governments around the world are starting to recognize the seriousness of this problem, introducing measures to curb pollution. However, considerable progress is still needed, and PM2.5 particles (those ≤2.5 µm) are of particular concern, not just in respiratory health but in a wider context.
Veravas, Inc., an emerging diagnostic company, launched a portfolio of products that can improve the accuracy of current diagnostic test results by helping laboratory professionals detect and manage biotin interference in patient samples with VeraTest Biotin and VeraPrep Biotin