Featured Laboratory Articles & Applications

  1. Downstream Process Development For Efficient Purification Of Adenovirus
    9/10/2018

    Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.

  2. How-To-Guide: Multiplexing Your Lateral Flow Assay
    6/5/2019

    There are numerous reasons why combining detection of multiple targets within a single assay is desirable. This guide outlines some of the important factors to consider when developing a multiplex LFA, be it from scratch or building on previously developed singleplex assays.

  3. The Role Of Water Filtration In Chemistry And Ecological Parameter Research
    10/4/2018

    A guide selecting the most relevant environmental parameters to study to retrieve the most useful information from collected samples.

  4. Better Biotherapeutic Characterization For Improved Quality Control
    5/23/2019

    Critical quality attributes (CQA) are fundamental to regulatory compliance and typically include data on how the candidate interacts with target proteins, size, and purity. In addition, information on process related CQA such as protein integrity, homogeneity, presence of host cell proteins, and DNA is required. This poster booklet provides a snapshot on how different analytical technologies have been used to look into aspects related to the efficacy, stability, and safety of therapeutic candidates.

  5. Scalable Process For Adenovirus Production
    8/3/2018

    This application note describes a process for adenovirus production, from upstream cell culture to downstream purification, using modern tools and technologies. 

  6. Avoid Pitfalls In HPLC Sample Prep Part 1
    1/30/2018

    Recognizing visible signs of in-system issues can identify potential problems and determine solutions that extend the usable lifetime of a column. Maximizing column lifetime has benefits in data quality, cost, and in reducing downtime.

  7. Improved Method for Determination of Adenovirus Concentration Using Surface Plasmon Resonance
    9/10/2018

    The performance of two assays for determination of adenovirus concentration based on surface plasmon resonance (SPR) is demonstrated in this application note.

  8. Using Flow Sensors As Diagnostic Tools In Pharmaceutical Manufacturing
    10/16/2018

    Investigating the source of this consumption increase early on and correcting the problem will improve the performance and uptime of all automated plant equipment.

  9. Simplify Soil Testing Workflows
    1/30/2018

    Working within a high-intensity environment, any strategy to simplify workflows can both relieve pressure on analysts and support data quality, improving lab efficiency and throughput.

  10. Optimization Of Midstream Cell Lysis And Virus Filtration Steps In An Adenovirus Purification Process
    9/10/2018

    Here we describe screening of detergents for release of adenovirus from HEK293 host cells to replace the traditionally used detergent Triton™.