AccuSizer 780 Single Particle Optical Sizer

The AccuSizer is the first fully automated high resolution particle sizing instrument in its class. It uses the principle of light obscuration to count and size particles one at a time. The dynamic range varies depending on the size of the sensor being used. The 780 provides the true particle size determination, it makes no assumptions about the shape of the distribution. Instead it builds the particle size distribution one particle at a time.

The AccuSizer 780/SPOS provides the "true" particle size distribution (PSD) by quickly sizing and counting large numbers of particles, one at a time. This approach is in sharp contrast to "ensemble" methods, such as Fraunhofer diffraction and sedimentation, which must process information produced by many particles simultaneously. These alternative techniques require the use of complex mathematical algorithms and can produce only a rough approximation of the true PSD, having limited sensitivity and very poor resolution. The 780 yields PSDs with resolution and accuracy comparable to those produced by the classical resistive-pore, or electrozone, method. However, it has a much wider size range, a much higher counting rate and is compatible with any liquid (or gas), and relatively immune to clogging.

The 780 clearly shows the important details in the size distribution which the other techniques usually miss. Single Particle Optical Sensing makes the meaurement accurate while Autodilution and innovative electronics make it fast and easy. With the AccuSizer 780 it is no longer necessary to trade accuracy and resolution for speed. The AccuSizer 780 can also be linked via a single computer to the Nicomp 380. This windows based software controller allows both instruments to work together so that the main peak of a sample may be analyzed by the 380.

Modules

780/SIS Syringe Injection Sampler
Combined with the 780, the SIS provides constant metered injection for the 780 Autodiluter. Large amounts of concentrated emulsions (TNA, drug delivery, food, soft drinks, paint, coatings, etc.) can be sized to provide accurate statistics on the tail of the distribution. Combined with special software, it is a comprehensive system for analysis of small and large volume injectables (SVI's/LVI's) as called for by USP.

780/DPF Dry Powder Feeder
The 780 can now handle dry powders - no more need for organic solvents. This module can easily be incorporated with existing AccuSizer units.

Particle Sizing Systems, 75 Aero Camino, Santa Barbara, CA 93117. Tel: 805-968-1497; Fax: 805-968-0361.