ARTICLES BY ANKE ROSCH
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![Couple driving in car-GettyImages-1320539830]( "Rats Behind The Wheel: The Right Preclinical Way To Investigate Drug Effects On Driving?")
Rats Behind The Wheel: The Right Preclinical Way To Investigate Drug Effects On Driving?12/8/2025What can we do preclinically for drug-induced impairment of driving ability? This article reviews the causes, regulatory environment, and limitations.
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![Pet Rat-GettyImages-1052049312]( "Should We Explore Suicidality In Animals During Preclinical Drug Development?")
Should We Explore Suicidality In Animals During Preclinical Drug Development?11/19/2024An adverse side effect for some drugs is suicidal ideation and behavior (SIB). Investigating SIB in animal studies represents the closest approximation to human SIB, yet the FDA Modernization Act 3.0 obligates us to reduce unnecessary animal testing. Let's examine this with data-driven research.
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![Rat-GettyImages-680037876]( "Animal Testing Isn't Perfect. Is There An Alternative?")
Animal Testing Isn't Perfect. Is There An Alternative?1/8/2024Statistics have been showing that rodent and non-rodent experiments predict human toxicity in only 48-71% of drugs. The FDA Modernization Act 2.0 of 2022 permits the use of suitable animal-free new approach methodologies, and the European Parliament launched a program to eliminate animal studies "as soon as scientifically possible." Let's take a data-driven, research-driven look at the topic.
Anke Rosch
Anke Rosch is a board-certified pharmacologist and toxicologist working at Boehringer Ingelheim Pharma GmbH & Co. KG. A doctor of veterinary medicine, she has more than 20 years of experience in the pharmaceutical industry and has special expertise in safety pharmacology. Anke can be reached at ankerosch.PharmacolTox@t-online.de.