1. A Buyer’s Guide To Cold Chain Temperature Monitoring Systems

    One of the great aspects of the modern world is that technology underpins everything, yet we don’t need to know anything about the technology.

  2. Systematic Method Development Of UPC2 Conditions Using Opioid Drugs

    This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

  3. A Single-Injection UPC2 Method For Fast And Simultaneous Separation Of Nine Fat-Soluble Vitamins

    Fat-soluble vitamins(FSVs) include vitamins A, D, E, K and carotenoids such as β-carotene. The FSVs are involved in complex metabolic reactions related to important biological functions such as vision (vitamin A), calcium absorption (vitamin D), antioxidant protection of cell membrane (vitamin E), and blood coagulation (vitamin K). By Rui Chen, Jinchuan Yang, and John McCauley, Waters Corporation

  4. Lipid Class Separation Using UPC2/MS

    A flexible, universal method was developed for the analysis of inter-class separations of neutral and amphipathetic lipids. By Michael D. Jones, Giorgis Isaac, Giuseppe Astarita, Andrew Aubin, John Shockcor, Vladimir Shulaev, Cristina Legido-Quigley, and Norman Smith

  5. Fast Separation Of Triacylglycerols In Oils Using UltraPerformance Convergence Chromatography (UPC2)

    Studies using UPC2 coupled with ultraviolet (UV) detection, mass spectrometry (MS), and evaporative light scattering (ELS) detection for the separation of triacylglycerols in tobacco, corn, sesame, and soybean seed oils are presented in this application note. By Mehdi Ashraf-Khorassani, Larry T. Taylor, Jinchuan Yang, and Giorgis Isaac

  6. Enantiomeric And Diasteriomeric Resolutions Of Chiral Pesticides By ACQUITY UPC2 With UV Detection

    In this application note we have shown the analysis of chiral pesticides using ACQUITY UPC2. ACQUITY UPC2 allows high efficiency separations that can significantly increase the sample throughput when compared with traditional normal-phase separations. By Marian Twohig, Andrew Aubin, Michael O’Leary, Tom DePhillipo, Sherry C. Perine, and David R. Stubbs

  7. Analysis Of Fat-Soluble Vitamin Capsules Using UltraPerformance Convergence Chromatography UPC2

    The use of UltraPerformance Convergence Chromatography (UPC2) in fat-soluble vitamin analysis provides a single viable technique that is cost-effective, sustainable, and a green technology alternative that lowers the use of organic solvents, provides fast analysis times, and maintains chromatographic data quality. By Andrew Aubin, Waters Corporation

  8. Fast And Simple Free Fatty Acids Analysis Using UPC2/MS

    The UPC2/MS FFA analysis described provides a simple and fast method with a significant reduction in analysis time compared to alternative techniques such as GC/MS, which requires FAME derivatization. By Giorgis Isaac, Michael D. Jones, Besnik Bajrami, Wassim Obeid, James Langridge, and Patrick Hatcher

  9. Bile Acid Profiling Using UltraPerformance Convergence Chromatography (UPC2) Coupled To ESI-MS/MS

    UltraPerformance Convergence Chromatography combined with ESI-MS/MS enabled the simultaneous profiling of 25 bile acids within 13 minutes. By Kaori Taguchi, Eiichiro Flukusaki, and Takeshi Bamba

  10. Qualitative And Quantitative Analysis Of Beta-Carotene Using UPC2

    A UPC2 method was successfully developed to separate the three most common carotenoids in less than two minutes.By Jacquelyn Runco, Lakshmi Subbarao, and Rui Chen, Waters Corporation

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