Novel Solid Phase Methodology Accelerates Peptide Synthesis

Kingston, UK - A technical poster, available from Activotec, describes a novel all-solid phase approach for synthesising cyclic peptide chitinase inhibitors as potential new leads for antifungal and anti-inflammatory drugs.

Based upon work by UK researchers from the Department of Pharmacy & Pharmacology, University of Bath and the College of Life Sciences, University of Dundee the poster describes how the entirely on-resin synthesis on the Activo-P11 Peptide Synthesizer delivers significant improvements in speed and efficiency over traditional approaches.

The Activo-P11 Peptide Synthesizer is an easy to use and affordable instrument for synthesis of very high quality peptides. The fully automated and enclosed system performs a wide range of chemistries to synthesise peptides of any length in the 0.1 - 1.0 mmol. scale. Combined with very easy-to-use software, designed by chemists for chemists, the Activo-P11 was one of the most visited attractions at the exhibition accompanying the symposium.

SOURCE: Activotec