Why Viral Particle Quantitation Matters

There are a variety of approaches for determining viral titer; many rely on measuring infectivity, genome copy number, or the amount of antigen present in a sample. However, these approaches do not directly quantify viral particles and may not recognize defective or noninfectious particles. Growing evidence demonstrates that the number of noninfectious viral particles in a sample is of significant biological importance and can impact both in vitro and in vivo studies. Now, rapid quantitation of the total number of viral particles in a sample is possible using the innovative ViroCyt® Virus Counter® platform.