News | January 7, 2021

Diagenode Launches Innovative Solution For Small RNA-Sequencing Compatible With MGI's DNBSE™ Equencers

Diagenode’s new D-Plex Small RNA DNBSEQ™ Kit incorporates unique D-Plex technology for library preparation enabling high performance with ultra low RNA inputs and providing diverse small RNA transcript detection

Denville, NJ and Liege, Belgium (PRWEB) - Diagenode, a leading global provider for complete solutions for sample preparation and epigenetics research, has launched a new small RNA-sequencing solution, D-Plex Small RNA DNBSEQ™ Kit , optimized and specifically formatted for MGI’s DNBSEQ sequencers.

Under the terms of a non-exclusive agreement signed earlier this year, the two companies collaborated to make Diagenode’s innovative D-Plex technology available on MGI’s platforms in a joint effort to promote solutions for advanced epigenetic discoveries.

The new D-Plex Small RNA DNBSEQ Kit is based on an innovative tailing and template switching technology, which delivers a ligation-free method for RNA library preparation from extremely low input amounts, down to 10 pg for small RNA. This technology also enables diverse and novel transcripts detection, ensuring realistic representation of the small non-coding RNA transcriptome and avoiding biased miRNA enrichment as with ligation methods. In addition, the new solution has been extensively validated for liquid biopsy, such as from human plasma, making it an important tool for clinically-relevant studies.

“The launch of the new D-Plex Small RNA DNBSEQ Kit reaffirms our commitment to forward progress in RNA research. This powerful solution combines our best-in-class RNA library preparation with MGI’s high-quality, cost-effective, DNA nanoballs sequencing solution, creating a unified platform to support high quality small RNA sequencing”, said Caroline Quolin, Ph.D., Product Manager at Diagenode. She expanded, “In addition, the kit requires only minimal hands-on time using a seamless one tube protocol. The library preparation itself requires just 5 hours.”

Dr. Yong Hou from MGI stated, “The DNBSEQ platform offers high accuracy, affordability and applications. We look forward to a continued expansion of our offerings with leading products like the Diagenode D-Plex small RNA-sequencing solution specifically optimized with our platform.”

The D-Plex Small RNA DNBSEQ Kit is available in a 24-reaction format with two sets of 24 DNBSEQ Barcodes available.

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About Diagenode
Diagenode is a leading provider of complete solutions for epigenetics research and sample preparation. The company has developed both shearing solutions for a number of applications as well as a comprehensive approach to gain new insights into epigenetics studies. The company offers innovative DNA and chromatin shearing and automation instruments, reagent kits, and high quality antibodies to streamline DNA methylation, ChIP, and ChIP-seq workflows. The company’s latest innovations include the industry’s most validated ChIP antibodies, D-Plex RNA sequencing with UMIs, and epigenetics assay services including scATAC-seq. For more information about Diagenode, please visit the company’s website at

About MGI
MGI, a member of global genomics leader BGI Group, is committed to building core tools and technology to lead life science through intelligent innovation. Based on its proprietary technology, MGI focuses on R&D, production and sales of sequencing instruments, reagents, and related products to support life science research, agriculture, precision medicine and healthcare. MGI is a leading producer of clinical high-throughput gene sequencers, and its multi-omics platforms include genetic sequencing, mass spectrometry, medical imaging and laboratory automation. Providing real-time, comprehensive, life-long solutions, its vision is to enable effective and affordable healthcare solutions for all.

Source: PRWeb

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