Application Note

Analysis Of Tricyclic Antidepressants In Human Urine Using Convergence Chromatography (UPC2)

Source: Waters Corporation

By Erin Chambers and Kenneth J Fountain, Waters Corporation

Charaterized by the use of an environmentally sustainable, renewable primary solvent (CO2), orthogonality to reversed phase chromatography, and availability of diverse stationary phases, UPC2 provides the benefits of reduced solvent consumption and cost, increased bioanalytical method selectivity, and flexibility in method development.