MiniZone Refiner

Design Scientific, Inc.

Zone refining is an attractive alternative to preparative chromatography

Details

Zone refining is an attractive alternative to preparative chromatography. This purification technique:

Requires no solvent selection

Requires no column selection

Uses no solvent

Sample is 100% recovered

Operates automatically

Sample sizes from 25 mg to 1 gram are easily purified

Requires only minutes to set up.

Chemicals that melt without decomposition and are at least partially crystalline are candidates for zone refining.

Applications include:

Preperation of Standards

Concentration of Impurities

Purification of Laser Dyes

Purification of Scintillation Materials

Purification of Organic Semiconductors

In Zone Refining, a short molten zone travels slowly through an elongated sample of a crystalline material. A molten zone traversing a solid sample has two liquid-solid interfaces; a melting interface and a freezing interface. At the melting interface the composition does not change but at the freezing interface, the impurities favor the liquid phase because the crystal structure tends to exclude molecules that do not readily fit into the crystal lattice. Passing the molten zone(s) through the sample many times concentrates the impurities at one end thereby purifying the sample.