By Dr. Henning Gieseler, PhD., Department of Pharmaceutics, University of Erlangen-Nuremberg
Freeze drying is generally known to be a time consuming, and therefore, expensive process. In order to lower costs during manufacturing, the effective cycle time must be reduced. This goal can be achieved by optimizing a freeze drying cycle in the laboratory — in particular the primary drying phase. Applying PAT in the laboratory can provide valuable information about product and process behavior and may help to identify the critical process parameters during cycle development and optimization.
When it comes to maintaining a lab washer for optimal use and results, it’s critical to clean and care for the machine properly. To avoid costly repairs and downtime, John Lubas, Miele Professional’s Service Manager, offers his best tips and advice.