FEATURED LABORATORY ARTICLES & APPLICATIONS

  • Systematic Method Development Of UPC2 Conditions Using Opioid Drugs

    This application note uses a panel of natural and synthetic opioid drugs to demonstrate the use of a systematic screening strategy for UPC2 method development. By Jonathan P. Danaceau, Kenneth J. Fountain, and Erin E. Chambers, Waters Corporation

  • A Single-Injection UPC2 Method For Fast And Simultaneous Separation Of Nine Fat-Soluble Vitamins

    Fat-soluble vitamins(FSVs) include vitamins A, D, E, K and carotenoids such as β-carotene. The FSVs are involved in complex metabolic reactions related to important biological functions such as vision (vitamin A), calcium absorption (vitamin D), antioxidant protection of cell membrane (vitamin E), and blood coagulation (vitamin K). By Rui Chen, Jinchuan Yang, and John McCauley, Waters Corporation

  • Lipid Class Separation Using UPC2/MS

    A flexible, universal method was developed for the analysis of inter-class separations of neutral and amphipathetic lipids. By Michael D. Jones, Giorgis Isaac, Giuseppe Astarita, Andrew Aubin, John Shockcor, Vladimir Shulaev, Cristina Legido-Quigley, and Norman Smith

  • Fast Separation Of Triacylglycerols In Oils Using UltraPerformance Convergence Chromatography (UPC2)

    Studies using UPC2 coupled with ultraviolet (UV) detection, mass spectrometry (MS), and evaporative light scattering (ELS) detection for the separation of triacylglycerols in tobacco, corn, sesame, and soybean seed oils are presented in this application note. By Mehdi Ashraf-Khorassani, Larry T. Taylor, Jinchuan Yang, and Giorgis Isaac

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